Measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis.

Isolation and characterization of a defective measles virus from brain biopsies of three patients in Iran with subacute sclerosing panencephalitis

Western blot analyses of measles virus antibody in normal persons and in patients with multiple sclerosis, subacute sclerosing panencephalitis, or atypical measles.

A version of the Western blot was developed to detect serum antibodies against measles virus polypeptides. With this technique, a seroepidemiological survey of antibodies to the several measles virus proteins in diverse measles-related conditions was conducted. The sera were obtained from individuals with a recent or long-past history of natural measles, from persons with a history of immunizat...

Subacute Sclerosing Panencephalitis in a Child with Recurrent Febrile Seizures

Subacute sclerosing panencephalitis (SSPE) is a devastating disease of the central nervous system (CNS) caused by persistent mutant measles virus infection. The diagnosis of SSPE is based on characteristic clinical and EEG findings and demonstration of elevated antibody titres against measles in cerebrospinal fluid. Subacute sclerosing panencephalitis can have atypical clinical features at the ...

Antibody response to structural proteins of measles virus in patients with natural measles and subacute sclerosing panencephalitis.

By immunoprecipitation and SDS-polyacrylamide gel electrophoresis, antibody responses to the structural proteins of measles virus were examined on patients with various forms of natural measles, atypical measles, and subacute sclerosing panencephalitis (SSPE). The serum of atypical measles most strongly reacted with four structural proteins, i.e., hemagglutinin (H), nucleocapsid (NC), fusion (F...

Immune complexes and visceral deposits of measles antigens in subacute sclerosing panencephalitis.

Immunofluorescence has been used to study visceral organs from a case of subacute sclerosing panencephalitis. Immune complexes were shown as granular deposits of IgG, complement, and measles antigens in renal glomeruli. Measles antigens were detected in the spleen, liver, and lymph nodes from many parts of the body.Immune-complex formation may be important in the aetiology of this disease and p...